Department of Health Science Care


Source:
 https://doi.org/10.1002/tox.23959 

Abstract

The consumption of contaminated finfish from the polluted river channel of Turag-Tongi-Balu, Kamarpara site, Dhaka poses significant health hazards to humans. We used mass spectrometry on chemically digested liquid samples from five fish species from Turag-Tongi-Balu to estimate the concentrations of 10 elements (Cr, Mn, Ni, Cu, Zn, As, Se, Cd, Fe, and Pb). Except M. vittatus, the mean concentrations of Cd, Mn, Pb, and Se exceeded the Food Safety Guideline (FSG) value in all fish species. Among the species studied, L. rohitaC. punctataC. batrachusH. fossilis, and M. vittatus exhibited higher Mn concentrations surpassing the FSG threshold, thus elevating the non-carcinogenic risk across all species. There were statistically significant differences (p < .05) in the mean concentrations of heavy metals among fish species. The Target Hazard Quotient (THQ) value of Mn poses a significant non-carcinogenic risk to human health, while the hazard of other metals is negligible. Except for M. vittus, the Hazard Index value (HI ≥ 1) revealed the risk that all metals exceed the limit and pose a threat to human health. Cd, As, and Ni metals pose a significant carcinogenic risk to human health from the consumption of fish samples, which is a particularly alarming target cancer risk (TCR). In conclusion, regular dietary consumption of fish from this polluted ecosystem of the Turag-Tongi-Balu River channel's Kamarpara site poses a significant health risk and is indicated as cancer. This study emphasizes the significance of monitoring heavy metal contamination in finfish and minimizing the risk to human health with effective measures.

Citation: Hossain, M.M., Jahan, I., Nahian, A. A., Zhu, D* (2024) Immediate health risk: concentration of heavy metals in contaminated freshwater fishes from the river channel of Turag-Tongi-Balu. Environmental Toxicology. 2023;39(1):120‐134. https://doi.org/10.1002/tox.23959 

 

 Abstract

The content of heavy metals in the food chain has grown due to human activities and rapid industrial growth. The accumulation of heavy metals in P. betel leaves and the related threat to human health were analyzed by using the AAS that was collected from eleven locations inside the city of Dhaka. High MDA contents indicated contamination in P. betel samples and can regulate biochemical activity by different potential toxic elements (PTEs). The P. betel samples revealed the highest mean concentrations of As (2.09mg/kg), Pb (0.06mg/kg), Mn (218mg/kg), Ni (1.55mg/kg), Cu (10mg/kg), Zn (2.6mg/kg), Cr (5.1mg/kg), and Cd (0.003mg/kg) and certain metal exceed the guideline value. Mn, Cr, and As mean values at the research sites are higher than the permitted concentration range. Among all metals, Mn was the most accumulated metal in leaves and enhanced hazard index (HI) and non-carcinogenic risk for children. Individual metal THQ values were all less than 1 (except Mn), indicating that consuming only one metal from betel samples would not pose a serious risk to one's health. However, HI value (> 1) indicates a possible non-carcinogenic health risk to urban city people, especially in children. The assessment revealed that the allowable range of Cr and As content in betel leaves may enhance the carcinogenic risk (CR). Among heavy metals, the CR value of Cr indicated an enhanced cancer risk in children at L3, L5, L6, L7, L8, L9, L10, and L11 sites. This study shows from a health perspective that people who eat contaminated betel leaves are continuously exposed to metal pollution, which can have both carcinogenic and noncarcinogenic effects.




Citation : Hossain M.M., Tripty, J., Shishir, M.Z.A., Han, S., Zhu, D*. (2024). Malondialdehyde and heavy metal contents in Piper betel: Possible Risks of Heavy Metals in Human Health. Journal of Food Composition and Analysis. https://doi.org/10.1016/j.jfca.2024.106540.






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